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72558-82-8

72558-82-8 structural image
Product Name: CeftazidiMe
Formula: C22H22N6O7S2
Synonyms: 1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinum;Ceftazidime pentahydrate
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CHEMICAL AND PHYSICAL PROPERTIES

Physical Description Solid
Melting Point 103-113
Solubility 5.73e-03 g/L
LogP -1.6
Chemical Classes Other Uses -> Pharmaceuticals

SAFETY INFORMATION

Signal word Danger
Pictogram(s)

Health Hazard
GHS08
GHS Hazard Statements H317:Sensitisation, Skin
H334:Sensitisation, respiratory
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P272:Contaminated work clothing should not be allowed out of the workplace.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P284:Wear respiratory protection.
P501:Dispose of contents/container to..…

COMPUTED DESCRIPTORS

Molecular Weight 546.6 g/mol
XLogP3 0.4
Hydrogen Bond Donor Count 3
Hydrogen Bond Acceptor Count 12
Rotatable Bond Count 8
Exact Mass 546.09913941 g/mol
Monoisotopic Mass 546.09913941 g/mol
Topological Polar Surface Area 245 Ų
Heavy Atom Count 37
Formal Charge 0
Complexity 1020
Isotope Atom Count 0
Defined Atom Stereocenter Count 2
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 1
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Ceftazidime is a third-generation cephalosporin antibiotic bearing pyridinium-1-ylmethyl and {[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It has a role as an antibacterial drug, an EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitor and a drug allergen. It is a cephalosporin and an oxime O-ether. It is a conjugate acid of a ceftazidime(1-).

RELATED SUPPLIERS

Medi Pharma Drug House

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PROTECH TELELINKS

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product:Ceftazidime 72558-82-8 98%
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