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70879-28-6

70879-28-6 structural image
Product Name: ALFENTANIL HYDROCHLORIDE CII (500 MG)
Formula: C21H35ClN6O4
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COMPUTED DESCRIPTORS

Molecular Weight 471.0 g/mol
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 7
Rotatable Bond Count 9
Exact Mass 470.2408313 g/mol
Monoisotopic Mass 470.2408313 g/mol
Topological Polar Surface Area 82 Ų
Heavy Atom Count 32
Formal Charge 0
Complexity 614
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 3
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Alfentanil Hydrochloride is the hydrochloride salt of alfentanil, a synthetic short-acting opioid with analgesic and local anesthesia enhancing activity. Alfentanil primarily binds to mu-opioid receptor, a G-protein-coupled receptor, thereby mimicking the actions of morphine, the prototypical mu receptor agonist. This agent induces anti-nociception responses mediated through inhibiting the release of various neurotransmitters such as substance P, GABA, dopamine, acetylcholine and noradrenaline; in addition, the release of vasopressin, somatostatin, insulin and glucagon are also inhibited.