COMPUTED DESCRIPTORS
| Molecular Weight | 1571.7 g/mol |
|---|---|
| Hydrogen Bond Donor Count | 23 |
| Hydrogen Bond Acceptor Count | 36 |
| Rotatable Bond Count | 38 |
| Exact Mass | 1570.5486639 g/mol |
| Monoisotopic Mass | 1570.5486639 g/mol |
| Topological Polar Surface Area | 779 Ų |
| Heavy Atom Count | 107 |
| Formal Charge | 0 |
| Complexity | 2820 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 20 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 2 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Peplomycin Sulfate is the sulfate salt of the bleomycin analogue peplomycin. Peplomycin forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals that cause single- and double-stranded breaks in DNA. This agent appears to show greater antitumor activity than bleomycin; its use is limited due to pulmonary toxicity. (NCI04)