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679809-58-6

Product Name: Enoxaparin sodium
Formula: C57H82N4Na4O53S3
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CHEMICAL AND PHYSICAL PROPERTIES

pH pH of injection is 5.5 to 7.5
Other Experimental Properties ... mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges

COMPUTED DESCRIPTORS

Molecular Weight 1322.0 g/mol
Hydrogen Bond Donor Count 13
Hydrogen Bond Acceptor Count 36
Rotatable Bond Count 17
Exact Mass 1321.1961300 g/mol
Monoisotopic Mass 1321.1961300 g/mol
Topological Polar Surface Area 612 Ų
Heavy Atom Count 86
Formal Charge 0
Complexity 2530
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 28
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 5
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Enoxaparin Sodium is the sodium salt of enoxaparin, a low molecular weight, synthetic heparin. As an anticoagulant/antithrombotic agent, enoxaprin's mechanism of action is similar to that of heparin, although it exhibits a higher ratio of anti-Factor Xa to anti-Factor IIa activity. This agent also has anti-inflammatory properties, inhibiting monocyte adhesion to tumor necrosis factor alpha- or lipopolysaccharide-activated endothelial cells. Compared to unfractionated heparins, the use of enoxaparin is associated with lower incidences of osteoporosis and heparin-induced thrombocytopenia.

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