CHEMICAL AND PHYSICAL PROPERTIES
pH | pH of injection is 5.5 to 7.5 |
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Other Experimental Properties | ... mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges |
COMPUTED DESCRIPTORS
Molecular Weight | 1322.0 g/mol |
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Hydrogen Bond Donor Count | 13 |
Hydrogen Bond Acceptor Count | 36 |
Rotatable Bond Count | 17 |
Exact Mass | 1321.1961300 g/mol |
Monoisotopic Mass | 1321.1961300 g/mol |
Topological Polar Surface Area | 612 Ų |
Heavy Atom Count | 86 |
Formal Charge | 0 |
Complexity | 2530 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 28 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 5 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Enoxaparin Sodium is the sodium salt of enoxaparin, a low molecular weight, synthetic heparin. As an anticoagulant/antithrombotic agent, enoxaprin's mechanism of action is similar to that of heparin, although it exhibits a higher ratio of anti-Factor Xa to anti-Factor IIa activity. This agent also has anti-inflammatory properties, inhibiting monocyte adhesion to tumor necrosis factor alpha- or lipopolysaccharide-activated endothelial cells. Compared to unfractionated heparins, the use of enoxaparin is associated with lower incidences of osteoporosis and heparin-induced thrombocytopenia.
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