66-81-9
Product Name:
Actidione
Formula:
C15H23NO4
Synonyms:
CHX;Actidione;Cycloheximide - CAS 66-81-9 - Calbiochem;Cycloheximide, High Purity - CAS 66-81-9 - Calbiochem;InSolution Cycloheximide - CAS 66-81-9 - Calbiochem
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Cycloheximide appears as colorless crystals. Used as a fungicide and as a anticancer drug. (EPA, 1998) |
|---|---|
| Color/Form | Plates from amyl acetate, water or 30% methanol |
| Melting Point | 247 to 250 °F (EPA, 1998) |
| Solubility | 10 to 50 mg/mL at 68 °F (NTP, 1992) |
| LogP | log Kow = 0.55 |
| Stability/Shelf Life | RELATIVELY HEAT AND ACID STABLE; RAPIDLY INACTIVATED AT ROOM TEMP BY DIL ALKALI WITH FORMATION OF A VOLATILE, FRAGRANT KETONE, 2,4-DIMETHYLCYCLOHEXANONE |
| Optical Rotation | Specific optical rotation: -3.38 deg @ 29 °C/D (9.47% in methanol); +6.8 deg @ 25 °C/D (2% in water) |
| Decomposition | When heated to decomposition it emits toxic fumes of /nitrogen oxides/. |
| Corrosivity | NONCORROSIVE |
| Other Experimental Properties | Elemental composition: C: 64.04%; H: 8.24%; N: 4.98%; O: 22.75% |
| Chemical Classes | Pesticides -> Plant Growth Regulators |
SAFETY INFORMATION
| Signal word | Danger |
|---|---|
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H341:Germ cell mutagenicity H412:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P273:Avoid release to the environment. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
COMPUTED DESCRIPTORS
| Molecular Weight | 281.35 g/mol |
|---|---|
| XLogP3 | 0.5 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 3 |
| Exact Mass | 281.16270821 g/mol |
| Monoisotopic Mass | 281.16270821 g/mol |
| Topological Polar Surface Area | 83.5 Ų |
| Heavy Atom Count | 20 |
| Formal Charge | 0 |
| Complexity | 404 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 4 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Cycloheximide appears as colorless crystals. Used as a fungicide and as a anticancer drug. (EPA, 1998)