66-76-2
Product Name:
DICUMAROL
Formula:
C19H12O6
Synonyms:
3,3ʹ-Methylenebis(4-hydroxycoumarin), Bishydroxycoumarin, Dicumarol;Bishydroxycoumarin;Dicoumarol;Dicoumarol - CAS 66-76-2 - Calbiochem;Dicumarol
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
Physical Description | White solid with a mild pleasant odor; [HSDB] |
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Color/Form | White or creamy white, crystalline powder |
Odor | Slight, pleasant odor |
Taste | Slightly bitter taste |
Melting Point | 290 °C |
Solubility | 128 mg/L |
LogP | 2.07 |
Decomposition | When heated to decomposition it emits acrid smoke and fumes. |
Collision Cross Section | 182 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards] |
Chemical Classes | Pesticides -> Rodenticides, Anticoagulant |
SAFETY INFORMATION
Signal word | Danger |
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Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08 Environment GHS09 |
GHS Hazard Statements |
H301:Acute toxicity,oral H372:Specific target organ toxicity, repeated exposure H411:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P273:Avoid release to the environment. P314:Get medical advice/attention if you feel unwell. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
COMPUTED DESCRIPTORS
Molecular Weight | 336.3 g/mol |
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XLogP3 | 2.6 |
Hydrogen Bond Donor Count | 2 |
Hydrogen Bond Acceptor Count | 6 |
Rotatable Bond Count | 2 |
Exact Mass | 336.06338810 g/mol |
Monoisotopic Mass | 336.06338810 g/mol |
Topological Polar Surface Area | 93.1 Ų |
Heavy Atom Count | 25 |
Formal Charge | 0 |
Complexity | 605 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Dicoumarol is a hydroxycoumarin that is methane in which two hydrogens have each been substituted by a 4-hydroxycoumarin-3-yl group. Related to warfarin, it has been used as an anticoagulant. It has a role as a vitamin K antagonist, an anticoagulant, an EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor and a Hsp90 inhibitor.