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62229-50-9

62229-50-9 structural image
Product Name: EPIDERMAL GROWTH FACTOR, HUMAN
Formula: C257H381N73O83S7
Synonyms: EGF;Epidermal Growth Factor;Epidermal Growth Factor, Human, Recombinant, E. coli;EGF, Human, Recombinant, E. coli;EGF, Murine Submaxillary Glands, Receptor Grade
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COMPUTED DESCRIPTORS

Molecular Weight 6046 g/mol
XLogP3 -19.6
Hydrogen Bond Donor Count 96
Hydrogen Bond Acceptor Count 96
Rotatable Bond Count 193
Exact Mass 6043.5948607 g/mol
Monoisotopic Mass 6041.5881511 g/mol
Topological Polar Surface Area 2560 Ų
Heavy Atom Count 420
Formal Charge 0
Complexity 15400
Isotope Atom Count 0
Defined Atom Stereocenter Count 51
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

A 6-kDa polypeptide growth factor initially discovered in mouse submaxillary glands. Human epidermal growth factor was originally isolated from urine based on its ability to inhibit gastric secretion and called urogastrone. Epidermal growth factor exerts a wide variety of biological effects including the promotion of proliferation and differentiation of mesenchymal and EPITHELIAL CELLS. It is synthesized as a transmembrane protein which can be cleaved to release a soluble active form.