CHEMICAL AND PHYSICAL PROPERTIES
Boiling Point | 741.3±60.0 |
---|---|
Melting Point | 156.1 |
Dissociation Constants | 12.58 |
COMPUTED DESCRIPTORS
Molecular Weight | 460.5 g/mol |
---|---|
XLogP3 | 1.8 |
Hydrogen Bond Donor Count | 1 |
Hydrogen Bond Acceptor Count | 7 |
Rotatable Bond Count | 8 |
Exact Mass | 460.13042228 g/mol |
Monoisotopic Mass | 460.13042228 g/mol |
Topological Polar Surface Area | 128 Ų |
Heavy Atom Count | 32 |
Formal Charge | 0 |
Complexity | 825 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 1 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Apremilast is a member of the class of isoindoles that is isoindole-1,3-dione substituted at position 4 by an acetamido group and at position 1 by a 1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl group. Used for treatment of psoriatic arthritis. It has a role as a phosphodiesterase IV inhibitor and a non-steroidal anti-inflammatory drug. It is an aromatic ether, a N-acetylarylamine, a sulfone and a member of phthalimides.
RELATED SUPPLIERS
KARPSCHEM LABORATORIES PVT. LTD.
1Y
product:608141-41-9 Apremilast
(S)-N-(2-(1-(3-ethoxy-4-methoxyphenyl)
-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide 96%