Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

Homecas57-27-2

57-27-2

57-27-2 structural image
Product Name: MORPHINE
Formula: C17H19NO3
Inquiry

CHEMICAL AND PHYSICAL PROPERTIES

Physical Description Solid
Color/Form Prisms
Odor Odorless
Taste Bitter
Boiling Point 190ºC
Melting Point 255 °C
Solubility 149 mg/L (at 20 °C)
Density 1.32 at 20 °C/4 °C
LogP 0.87
Stability/Shelf Life When exposed to air, morphine sulfate gradually loses its water of hydration. The drug darkens on prolonged exposure to light.
Optical Rotation Yellowish-white powder; slight acetic odor. Specific optical rotation (15 °C): 77 deg (water). One g dissolves in 2.25 m: water, 2 m\L boiling water, 22 mL alcohol, 2 mL alcohol at 60 °C, 4.5 mL glycerol, 4.75 mL chloroform. Practically insoluble in ether. /Acetate trihydrate/
Decomposition When heated to decomposition it emits toxic fumes of /nitrogen oxide/.
pH pH of saturated solution: 8.5
Dissociation Constants 8.18
Collision Cross Section 164 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]
Other Experimental Properties Occurs as the trihydrate. White flakes or crystalline powder; bitter taste. Loses its water of crystallization at about 100 °C and usually becomes yellowish. MP: about 200 °C (decomposes). Specific optical rotation: -113.5 deg at 25 °C/D (c = 2.2 in H2O). One gram dissolves in 17.5 mL water, 0.5 mL boiling water, 52 mL alcohol, 6 mL alcohol at 60 °C; slowly soluble in glycerol. Insoluble in chloroform, ether. pH about 5 /Morphine hydrochloride/
Chemical Classes Biological Agents -> Plant Toxins

SAFETY INFORMATION

Signal word Danger
Pictogram(s)

Flame
Flammables
GHS02

Skull and Crossbones
Acute Toxicity
GHS06

Health Hazard
GHS08
GHS Hazard Statements H225:Flammable liquids
H370:Specific target organ toxicity, single exposure
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P370+P378:In case of fire: Use … for extinction.
P403+P235:Store in a well-ventilated place. Keep cool.

COMPUTED DESCRIPTORS

Molecular Weight 285.34 g/mol
XLogP3 0.8
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 0
Exact Mass 285.13649347 g/mol
Monoisotopic Mass 285.13649347 g/mol
Topological Polar Surface Area 52.9 Ų
Heavy Atom Count 21
Formal Charge 0
Complexity 494
Isotope Atom Count 0
Defined Atom Stereocenter Count 5
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Morphine is a morphinane alkaloid that is a highly potent opiate analgesic psychoactive drug. Morphine acts directly on the central nervous system (CNS) to relieve pain but has a high potential for addiction, with tolerance and both physical and psychological dependence developing rapidly. Morphine is the most abundant opiate found in Papaver somniferum (the opium poppy). It has a role as an opioid analgesic, a mu-opioid receptor agonist, a plant metabolite, an environmental contaminant, a xenobiotic, a vasodilator agent, an anaesthetic, a drug allergen and a geroprotector. It is an organic heteropentacyclic compound, a tertiary amino compound and a morphinane alkaloid. It is a conjugate base of a morphine(1+). It derives from a hydride of a morphinan.