55096-26-9
Product Name:
Nalmefene
Formula:
C21H25NO3
Synonyms:
(5α)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinan-3,14-diol
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CHEMICAL AND PHYSICAL PROPERTIES
| Color/Form | Crystals from ethyl acetate |
|---|---|
| Melting Point | 105-110 °C |
| Stability/Shelf Life | Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. |
| Dissociation Constants | 7.6 |
| Other Experimental Properties | MW: 375.9. White to off-white crystalline powder ... freely soluble in water up to 130 mg/L and slightly soluble in chloroform up to 0.13 mg/mL ... no longer available in the US /Revex/ |
SAFETY INFORMATION
| Signal word | Warning |
|---|---|
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
COMPUTED DESCRIPTORS
| Molecular Weight | 339.4 g/mol |
|---|---|
| XLogP3 | 2.7 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 2 |
| Exact Mass | 339.18344366 g/mol |
| Monoisotopic Mass | 339.18344366 g/mol |
| Topological Polar Surface Area | 52.9 Ų |
| Heavy Atom Count | 25 |
| Formal Charge | 0 |
| Complexity | 618 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 4 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Nalmefene is a morphinane alkaloid.