41294-56-8
Product Name:
Alfacalcidol
Formula:
C27H44O2
Synonyms:
1α-Hydroxycholecalciferol;1α-Hydroxyvitamin D3;1α-OH-D₃;Alfacalcidol;Vitamin D₃, 1α-Hydroxy- - CAS 41294-56-8 - Calbiochem
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
Physical Description | Solid |
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Melting Point | 136 °C |
Solubility | <1 mg/mL |
SAFETY INFORMATION
Signal word | Danger |
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Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 |
GHS Hazard Statements |
H300:Acute toxicity,oral |
COMPUTED DESCRIPTORS
Molecular Weight | 400.6 g/mol |
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XLogP3 | 6.8 |
Hydrogen Bond Donor Count | 2 |
Hydrogen Bond Acceptor Count | 2 |
Rotatable Bond Count | 6 |
Exact Mass | 400.334130642 g/mol |
Monoisotopic Mass | 400.334130642 g/mol |
Topological Polar Surface Area | 40.5 Ų |
Heavy Atom Count | 29 |
Formal Charge | 0 |
Complexity | 643 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 6 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 2 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Alfacalcidol is a member of the class of D3 vitamins that is calciol in which the hydrogen at the 1alpha position is replaced by a hydroxy group. It is an active metabolite of cholecalciferol, which performs important functions in regulation of the calcium balance and the bone metabolism. It has a role as a bone density conservation agent. It is a member of D3 vitamins, a seco-cholestane, a hydroxycalciol and a diol. It is functionally related to a calciol.