COMPUTED DESCRIPTORS
Molecular Weight | 326.35 g/mol |
---|---|
XLogP3 | -0.9 |
Hydrogen Bond Donor Count | 3 |
Hydrogen Bond Acceptor Count | 6 |
Rotatable Bond Count | 6 |
Exact Mass | 326.15901982 g/mol |
Monoisotopic Mass | 326.15901982 g/mol |
Topological Polar Surface Area | 141 Ų |
Heavy Atom Count | 23 |
Formal Charge | 0 |
Complexity | 533 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 4 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Valtorcitabine is an orally active prodrug of torcitabine (L-deoxycytidine), a nucleoside analog with activity against hepatitis B virus. Torcitabine is modified in vivo to its triphosphate form and acts as a competitive inhibitor of viral DNA polymerase.