3736-81-0
Product Name:
Diloxanide furoate
Formula:
C14H11Cl2NO4
Synonyms:
2,2-Dichloro-N-(4-hydroxyphenyl)-N-methylacetamide 2-furoic acid ester
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
Physical Description | Solid |
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Solubility | >49.2 [ug/mL] (The mean of the results at pH 7.4) |
Collision Cross Section | 171.7 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards] |
SAFETY INFORMATION
Signal word | Warning |
---|---|
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral |
COMPUTED DESCRIPTORS
Molecular Weight | 328.1 g/mol |
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XLogP3 | 3.4 |
Hydrogen Bond Donor Count | 0 |
Hydrogen Bond Acceptor Count | 4 |
Rotatable Bond Count | 5 |
Exact Mass | 327.0065132 g/mol |
Monoisotopic Mass | 327.0065132 g/mol |
Topological Polar Surface Area | 59.8 Ų |
Heavy Atom Count | 21 |
Formal Charge | 0 |
Complexity | 383 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Diloxanide furoate is a carboxylic ester resulting from the formal condensation of the carboxy group of furan-2-carboxylic acid with the hydroxy group of 2,2-dichloro-N-(4-hydroxyphenyl)-N-methylacetamide. It is a drug used for the treatment of asymptomatic amebiasis. It has a role as an antiamoebic agent and a prodrug. It is a member of furans, a carboxylic ester, a tertiary carboxamide and an organochlorine compound.