COMPUTED DESCRIPTORS
Molecular Weight | 1242.3 g/mol |
---|---|
Hydrogen Bond Donor Count | 17 |
Hydrogen Bond Acceptor Count | 17 |
Rotatable Bond Count | 31 |
Exact Mass | 1241.59415488 g/mol |
Monoisotopic Mass | 1241.59415488 g/mol |
Topological Polar Surface Area | 512 Ų |
Heavy Atom Count | 89 |
Formal Charge | 0 |
Complexity | 2420 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 8 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 2 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
A decapeptide that stimulates the synthesis and secretion of both pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE. GnRH is produced by neurons in the septum PREOPTIC AREA of the HYPOTHALAMUS and released into the pituitary portal blood, leading to stimulation of GONADOTROPHS in the ANTERIOR PITUITARY GLAND.