145781-92-6
Product Name:
Goserelin acetate
Formula:
C61H88N18O16
Synonyms:
[D-Ser(tBu)6,Azagly10]-LHRH acetate salt;Goserelin acetate
Inquiry
SAFETY INFORMATION
| Signal word | Danger |
|---|---|
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H360:Reproductive toxicity |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P280:Wear protective gloves/protective clothing/eye protection/face protection. P308+P313:IF exposed or concerned: Get medical advice/attention. P405:Store locked up. P501:Dispose of contents/container to..… |
COMPUTED DESCRIPTORS
| Molecular Weight | 1329.5 g/mol |
|---|---|
| Hydrogen Bond Donor Count | 18 |
| Hydrogen Bond Acceptor Count | 18 |
| Rotatable Bond Count | 32 |
| Exact Mass | 1328.66256879 g/mol |
| Monoisotopic Mass | 1328.66256879 g/mol |
| Topological Polar Surface Area | 533 Ų |
| Heavy Atom Count | 95 |
| Formal Charge | 0 |
| Complexity | 2590 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 9 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 2 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Goserelin Acetate is the acetate salt of a synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH). Continuous, prolonged administration of goserelin in males results in inhibition of pituitary gonadotropin secretion, leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production. (NCI04)