COMPUTED DESCRIPTORS
Molecular Weight | 464.0 g/mol |
---|---|
Hydrogen Bond Donor Count | 2 |
Hydrogen Bond Acceptor Count | 6 |
Rotatable Bond Count | 6 |
Exact Mass | 463.1332552 g/mol |
Monoisotopic Mass | 463.1332552 g/mol |
Topological Polar Surface Area | 96.4 Ų |
Heavy Atom Count | 31 |
Formal Charge | 0 |
Complexity | 601 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 2 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Moricizine Hydrochloride is the hydrochloride salt form of moricizine, a phenothiazine analog with class I antiarrhythmic activity. Moricizine hydrochloride blocks the rapid flow of sodium ions into the myocardial cell during phase 0 of the action potential. This decreases excitability, slows the impulse conduction through the atrioventricular (AV) node and depresses depolarization.