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27833-64-3

27833-64-3 structural image
Product Name: Loxapine succinate salt
Formula: C22H24ClN3O5
Synonyms: Loxapine succinate salt
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CHEMICAL AND PHYSICAL PROPERTIES

Collision Cross Section 176.4 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

COMPUTED DESCRIPTORS

Molecular Weight 445.9 g/mol
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 7
Rotatable Bond Count 4
Exact Mass 445.1404486 g/mol
Monoisotopic Mass 445.1404486 g/mol
Topological Polar Surface Area 103 Ų
Heavy Atom Count 31
Formal Charge 0
Complexity 542
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 2
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Loxapine Succinate is the succinate salt form of loxapine, a tricyclic dibenzoxazepine antipsychotic agent with antiemetic, sedative, anticholinergic, and antiadrenergic actions. Loxapine succinate exerts its actions by blocking the dopamine receptors at postsynaptic receptor sites in the limbic system, cortical system and basal ganglia, thereby reducing the hallucinations and delusions that are associated with schizophrenia. This agent also exerts extrapyramidal side effects.

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Centaur Pharmaceuticals Pvt Ltd

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