COMPUTED DESCRIPTORS
Molecular Weight | 534.6 g/mol |
---|---|
XLogP3 | -2.4 |
Hydrogen Bond Donor Count | 5 |
Hydrogen Bond Acceptor Count | 13 |
Rotatable Bond Count | 6 |
Exact Mass | 534.11037280 g/mol |
Monoisotopic Mass | 534.11037280 g/mol |
Topological Polar Surface Area | 257 Ų |
Heavy Atom Count | 36 |
Formal Charge | 0 |
Complexity | 1100 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 3 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 2 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Ceftobiprole is a fifth-generation cephalosporin antibiotic having (E)-[(3'R)-2-oxo[1,3'-bipyrrolidin]-3-ylidene]methyl and [(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetyl]amino side groups located at positions 3 and 7 respectively; developed for the treatment of hospital-acquired pneumonia (HAP, excluding ventilator-associated pneumonia, VAP) and community-acquired pneumonia (CAP). It has a role as an antimicrobial agent. It is a cephalosporin and a member of thiadiazoles.