CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Solid |
|---|---|
| Melting Point | 230 °C as HCl salt |
| Solubility | 35.5 mg/mL at 25 °C as HCl salt |
| LogP | 1.4 |
| Dissociation Constants | 8.71 and 9.96 (hcl form) |
COMPUTED DESCRIPTORS
| Molecular Weight | 357.4 g/mol |
|---|---|
| XLogP3 | 0.2 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 2 |
| Exact Mass | 357.19400834 g/mol |
| Monoisotopic Mass | 357.19400834 g/mol |
| Topological Polar Surface Area | 73.2 Ų |
| Heavy Atom Count | 26 |
| Formal Charge | 0 |
| Complexity | 597 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 5 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Nalbuphine is an organic heteropentacyclic compound. It has a role as a mu-opioid receptor antagonist and an opioid analgesic. It derives from a hydride of a morphinan.