CHEMICAL AND PHYSICAL PROPERTIES
| Collision Cross Section | 613.37 Ų [M+2H]2+ [CCS Type: DT, Method: stepped-field] |
|---|
SAFETY INFORMATION
| Signal word | Danger |
|---|---|
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
COMPUTED DESCRIPTORS
| Molecular Weight | 2846.5 g/mol |
|---|---|
| XLogP3 | -2.7 |
| Hydrogen Bond Donor Count | 41 |
| Hydrogen Bond Acceptor Count | 37 |
| Rotatable Bond Count | 99 |
| Exact Mass | 2845.7575265 g/mol |
| Monoisotopic Mass | 2844.7541717 g/mol |
| Topological Polar Surface Area | 1150 Ų |
| Heavy Atom Count | 201 |
| Formal Charge | 0 |
| Complexity | 6300 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 28 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Melittin is a 26-membered polypeptide consisting of Gly, Ile, Gly, Ala, Val, Leu, Lys, Val, Leu, Thr, Thr, Gly, Leu, Pro, Ala, Leu, Ile, Ser, Trp, Ile, Lys, Arg, Lys, Arg, Gln and Gln-NH2 residues joined in sequence. It is the principal active component of bee venom. It has a role as an animal metabolite, a venom, an EC 2.7.11.13 (protein kinase C) inhibitor, a hepatoprotective agent, an apoptosis inducer, a neuroprotective agent and an antineoplastic agent. It is a polypeptide and a peptidyl amide.