17650-98-5
Product Name:
CAERULEIN
Formula:
C58H73N13O21S2
Synonyms:
[Tyr(SO3H)4]Caerulein;Caerulein Sulfated;Cerulein;Ceruletide;pGlu-Gln-Asp-Tyr(SO3H)-Thr-Gly-Trp-Met-Asp-Phe-NH2
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Solid |
|---|---|
| Solubility | 1.16e-02 g/L |
| LogP | -0.9 |
COMPUTED DESCRIPTORS
| Molecular Weight | 1352.4 g/mol |
|---|---|
| XLogP3 | -3 |
| Hydrogen Bond Donor Count | 17 |
| Hydrogen Bond Acceptor Count | 22 |
| Rotatable Bond Count | 38 |
| Exact Mass | 1351.44853874 g/mol |
| Monoisotopic Mass | 1351.44853874 g/mol |
| Topological Polar Surface Area | 585 Ų |
| Heavy Atom Count | 94 |
| Formal Charge | 0 |
| Complexity | 2840 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 10 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Ceruletide is a decapeptide comprising 5-oxoprolyl, glutamyl, aspartyl, O-sulfotyrosyl, threonyl, glycyl, tryptopyl, methionyl, aspartyl and phenylalaninamide residues in sequence. Found in the skins of certain Australian amphibians, it is an analogue of the gastrointestinal peptide hormone cholecystokinin and stimulates gastric, biliary, and pancreatic secretion. It is used in cases of paralysis of the intestine (paralytic ileus) and as a diagnostic aid in pancreatic malfunction. It has a role as a diagnostic agent and a gastrointestinal drug.