CHEMICAL AND PHYSICAL PROPERTIES
| Color/Form | White solid from ethyl acetate + heptane |
|---|---|
| Melting Point | 86-89 °C |
| Solubility | Insoluble |
| LogP | 6.9 |
| Optical Rotation | Specific optical rotation (in ethanol): +20 deg at 25 °C/D |
COMPUTED DESCRIPTORS
| Molecular Weight | 602.7 g/mol |
|---|---|
| XLogP3 | 7 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 10 |
| Rotatable Bond Count | 11 |
| Exact Mass | 602.20622782 g/mol |
| Monoisotopic Mass | 602.20622782 g/mol |
| Topological Polar Surface Area | 114 Ų |
| Heavy Atom Count | 42 |
| Formal Charge | 0 |
| Complexity | 1050 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 2 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Tipranavir is a pyridine-2-sulfonamide substituted at C-5 by a trifluoromethyl group and at the sulfonamide nitrogen by a dihydropyrone-containing m-tolyl substituent. It is an HIV-1 protease inhibitor. It has a role as a HIV protease inhibitor and an antiviral drug.