CHEMICAL AND PHYSICAL PROPERTIES
Melting Point | Sodium salt decomposes at 240 °C |
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LogP | 2.3 |
Caco2 Permeability | -6.96 |
COMPUTED DESCRIPTORS
Molecular Weight | 302.24 g/mol |
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XLogP3 | 3.1 |
Hydrogen Bond Donor Count | 4 |
Hydrogen Bond Acceptor Count | 8 |
Rotatable Bond Count | 4 |
Exact Mass | 302.05388604 g/mol |
Monoisotopic Mass | 302.05388604 g/mol |
Topological Polar Surface Area | 140 Ų |
Heavy Atom Count | 22 |
Formal Charge | 0 |
Complexity | 415 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Olsalazine is an azobenzene that consists of two molecules of 4-aminosalicylic acid joined by an azo linkage. A prodrug for mesalazine, an anti-inflammatory drug, it is used (as the disodium salt) in the treatment of inflammatory bowel disease. It has a role as a prodrug and a non-steroidal anti-inflammatory drug. It is a dicarboxylic acid and a member of azobenzenes. It is functionally related to a salicylic acid. It is a conjugate acid of an olsalazine(2-).