15183-37-6
Product Name:
ESTETROL
Formula:
C18H24O4
Synonyms:
15α-Hydroxyestriol;3,15α,16α,17β-Tetrahydroxyestra-1,3,5(10)-triene;E4;Estra-1,3,5(10)-triene-3,15α,16α,17β-tetrol;Oestetrol
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Boiling Point | 491.9±45.0 |
|---|---|
| Melting Point | 233-236 |
| LogP | 2.62 |
| Dissociation Constants | 10.22±0.70 |
COMPUTED DESCRIPTORS
| Molecular Weight | 304.4 g/mol |
|---|---|
| XLogP3 | 1.5 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 0 |
| Exact Mass | 304.16745924 g/mol |
| Monoisotopic Mass | 304.16745924 g/mol |
| Topological Polar Surface Area | 80.9 Ų |
| Heavy Atom Count | 22 |
| Formal Charge | 0 |
| Complexity | 441 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 7 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Estetrol is a 3-hydroxy steroid that is 17beta-estradiol which has been substituted at the 15alpha and 16alpha positions by two additional hydroxy groups. It is a natural estrogen produced exclusively during pregnancy by the fetal liver. It has a role as an estrogen, an estrogen receptor agonist, a human metabolite, a human xenobiotic metabolite and an oral contraceptive. It is a 3-hydroxy steroid, a 17beta-hydroxy steroid, a 16alpha-hydroxy steroid, a 15alpha-hydroxy steroid and a steroid hormone. It derives from a hydride of an estrane.