138977-28-3
Product Name:
CAPSAZEPINE
Formula:
C19H21ClN2O2S
Synonyms:
Capsazepine - CAS 138977-28-3 - Calbiochem;N-[2-(4-Chlorophenyl)ethyl]-1,3,4,5-tetrahydro-7,8-dihydroxy-2H-2-benzazepine-2-carbothioamide
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COMPUTED DESCRIPTORS
Molecular Weight | 376.9 g/mol |
---|---|
XLogP3 | 3.9 |
Hydrogen Bond Donor Count | 3 |
Hydrogen Bond Acceptor Count | 3 |
Rotatable Bond Count | 3 |
Exact Mass | 376.1012268 g/mol |
Monoisotopic Mass | 376.1012268 g/mol |
Topological Polar Surface Area | 87.8 Ų |
Heavy Atom Count | 25 |
Formal Charge | 0 |
Complexity | 445 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Capsazepine is a benzazepine that is 2,3,4,5-tetrahydro-1H-2-benzazepine which is substituted by hydroxy groups at positions 7 and 8 and on the nitrogen atom by a 2-(p-chlorophenyl)ethylaminothiocarbonyl group. A synthetic analogue of capsaicin, it was the first reported capsaicin receptor antagonist. It has a role as a capsaicin receptor antagonist. It is a member of catechols, a member of thioureas, a benzazepine and a member of monochlorobenzenes.