130-26-7
Product Name:
Clioquinol
Formula:
C9H5ClINO
Synonyms:
5-Chloro-7-iodo-8-hydroxyquinoline;5-Chloro-7-iodo-8-quinolinol;5-Chloro-8-hydroxy-7-iodoquinoline;Clioquinol;Iodochlorhydroxyquin
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
Physical Description | Iodochlorohydroxyquinoline is a cream-colored to brownish-yellow powder. Practically odorless. Decomposes at 178-179 °C. Used as a topical anti-infective. |
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Color/Form | Brownish-yellow, bulky powder |
Odor | Practically odorless |
Melting Point | 352 to 354 °F (NTP, 1992) |
Solubility | 0.8 [ug/mL] (The mean of the results at pH 7.4) |
Stability/Shelf Life | Clioquinol darkens on exposure to light. |
Decomposition | When heated to decomposition it emits very toxic fumes of /hydrogen chloride, hydrogen iodide and nitrogen oxides/. |
Collision Cross Section | 138.2 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards] |
Other Experimental Properties | Decompose at about 178-179 °C |
Chemical Classes | Other Uses -> Pharmaceuticals |
SAFETY INFORMATION
Signal word | Danger |
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Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 |
GHS Hazard Statements |
H301:Acute toxicity,oral H315:Skin corrosion/irritation H317:Sensitisation, Skin H319:Serious eye damage/eye irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
COMPUTED DESCRIPTORS
Molecular Weight | 305.50 g/mol |
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XLogP3 | 3.5 |
Hydrogen Bond Donor Count | 1 |
Hydrogen Bond Acceptor Count | 2 |
Rotatable Bond Count | 0 |
Exact Mass | 304.91044 g/mol |
Monoisotopic Mass | 304.91044 g/mol |
Topological Polar Surface Area | 33.1 Ų |
Heavy Atom Count | 13 |
Formal Charge | 0 |
Complexity | 193 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Iodochlorohydroxyquinoline is a cream-colored to brownish-yellow powder. Practically odorless. Decomposes at 178-179 °C. Used as a topical anti-infective.