129-46-4
Product Name:
Suramin sodium
Formula:
C51H34N6Na6O23S6
Synonyms:
P2Y Antagonist I, Purinergic Receptor P2Y Antagonist I, PTP Inhibitor VI;PTP Inhibitor VI, Purinergic Receptor P2Y Antagonist I, P2Y Antagonist I;Suramin, Sodium Salt - CAS 129-46-4 - Calbiochem;Suramine sodium salt
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Solubility | Water Very soluble (mg/mL) |
|---|
COMPUTED DESCRIPTORS
| Molecular Weight | 1429.2 g/mol |
|---|---|
| Hydrogen Bond Donor Count | 6 |
| Hydrogen Bond Acceptor Count | 23 |
| Rotatable Bond Count | 10 |
| Exact Mass | 1427.9385741 g/mol |
| Monoisotopic Mass | 1427.9385741 g/mol |
| Topological Polar Surface Area | 551 Ų |
| Heavy Atom Count | 92 |
| Formal Charge | 0 |
| Complexity | 2940 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 7 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Suramin sodium is an organic sodium salt that is the hexasodium salt of suramin. It is an FDA approved drug for African sleeping sickness and river blindness. It has a role as an antinematodal drug, a trypanocidal drug, an antineoplastic agent, an angiogenesis inhibitor, an apoptosis inhibitor, an EC 2.7.11.13 (protein kinase C) inhibitor, a GABA antagonist, a GABA-gated chloride channel antagonist, a purinergic receptor P2 antagonist and a ryanodine receptor agonist. It contains a suramin(6-).