128270-60-0
Product Name:
Bivalirudin
Formula:
C98H138N24O33
Synonyms:
;Hirulog trifluoroacetate salt
Inquiry
SAFETY INFORMATION
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
COMPUTED DESCRIPTORS
| Molecular Weight | 2180.3 g/mol |
|---|---|
| XLogP3 | -7.1 |
| Hydrogen Bond Donor Count | 28 |
| Hydrogen Bond Acceptor Count | 35 |
| Rotatable Bond Count | 67 |
| Exact Mass | 2179.9891678 g/mol |
| Monoisotopic Mass | 2178.9858129 g/mol |
| Topological Polar Surface Area | 902 Ų |
| Heavy Atom Count | 155 |
| Formal Charge | 0 |
| Complexity | 4950 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 16 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Bivalirudin is a synthetic peptide of 20 amino acids, comprising D-Phe, Pro, Arg, Pro, Gly, Gly, Gly, Gly, Asn, Gly, Asp, Phe, Glu, Glu, Ile, Pro, Glu, Glu, Tyr, and Leu in sequence. A congener of hirudin (a naturally occurring drug found in the saliva of the medicinal leech), it a specific and reversible inhibitor of thrombin, and is used as an anticoagulant. It has a role as an anticoagulant and an EC 3.4.21.5 (thrombin) inhibitor.