CHEMICAL AND PHYSICAL PROPERTIES
| Color/Form | Hygroscopic powder |
|---|---|
| Melting Point | 124 °C |
| Solubility | Freely soluble in water |
| Density | 1.22 g/mL at 20 °C |
| Optical Rotation | Specific optical rotation: -26.9 deg at 20 °C/365 °C (c = 1.45 in water) |
| Viscosity | 9.2 mPa.sec at 20 °C; 5.3 mPa.sec at 37 °C |
| Other Experimental Properties | Supplied as a sterile, non-pyrogenic, clear, colorless aqueous solution /Multihance/ |
COMPUTED DESCRIPTORS
| Molecular Weight | 513.5 g/mol |
|---|---|
| XLogP3 | -7.1 |
| Hydrogen Bond Donor Count | 5 |
| Hydrogen Bond Acceptor Count | 14 |
| Rotatable Bond Count | 20 |
| Exact Mass | 513.19585881 g/mol |
| Monoisotopic Mass | 513.19585881 g/mol |
| Topological Polar Surface Area | 205 Ų |
| Heavy Atom Count | 36 |
| Formal Charge | 0 |
| Complexity | 727 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Gadobenate Dimeglumine is a gadolinium-based paramagnetic contrast agent. When placed in a magnetic field, gadobenate dimeglumine produces a large magnetic moment and so a large local magnetic field, which can enhance the relaxation rate of nearby protons; as a result, the signal intensity of tissue images observed with magnetic resonance imaging (MRI) may be enhanced. Because this agent is preferentially taken up by normal functioning hepatocytes, normal hepatic tissue is enhanced with MRI while tumor tissue is unenhanced. In addition, because gadobenate dimeglumine is excreted in the bile, it may be used to visualize the biliary system using MRI.