CHEMICAL AND PHYSICAL PROPERTIES
| Color/Form | White to slightly yellow powder |
|---|---|
| Melting Point | approximately 200 °C |
| Other Experimental Properties | Hygroscopic |
COMPUTED DESCRIPTORS
| Molecular Weight | 1022.2 g/mol |
|---|---|
| XLogP3 | 4.2 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 14 |
| Rotatable Bond Count | 10 |
| Exact Mass | 1021.47316054 g/mol |
| Monoisotopic Mass | 1021.47316054 g/mol |
| Topological Polar Surface Area | 257 Ų |
| Heavy Atom Count | 73 |
| Formal Charge | 0 |
| Complexity | 2010 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 9 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Quinupristin/dalfopristin is a combination of two antibiotics used to treat infections by staphylococci and by vancomycin-resistant Enterococcus faecium. Dalfopristin inhibits the early phase of protein synthesis in the bacterial ribosome and quinupristin inhibits the late phase of protein synthesis. The combination of the two components acts synergistically and is more effective in vitro than each component alone.