CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Tetraethyl pyrophosphate is an organic phosphate pesticide which acts as an inhibitor of cholinesterase, and as such it is highly toxic by all routes of exposure. It is a water-white to amber liquid, depending on purity. Tetraethyl pyrophosphate is soluble in water and is slowly decomposed by water. It is toxic by inhalation and by skin absorption. It may be found as a liquid or as a dry mixture where the liquid is absorbed onto a dry carrier. |
|---|---|
| Color/Form | Mobile liquid |
| Odor | Agreeable odor |
| Boiling Point | 280 °F at 2.3 mmHg (EPA, 1998) |
| Melting Point | 32 °F (EPA, 1998) |
| Flash Point | >110 °C c.c. |
| Solubility | Miscible (decomposes) (NTP, 1992) |
| Density | 1.185 at 68 °F (EPA, 1998) - Denser than water; will sink |
| Vapor Density | Relative vapor density (air = 1): 10 |
| Vapor Pressure | 0.00047 mmHg at 86 °F (EPA, 1998) |
| LogP | 2.94 |
| Henry's Law Constant | Henry's Law constant = 2.2X10-10 atm-cu m/mol at 25 °C /Estimated/ |
| Stability/Shelf Life | Quickly hydrolyzed by water (half-life at 25 °C about 7 hr in a 50% vol/vol mixt). |
| Decomposition | When heated to decomposition it emits highly toxic fumes of /phosphorus oxides/. |
| Corrosivity | TEPP will attack some forms of plastics, rubber, and coatings. |
| Refractive Index | Index of refraction: 1.4196 @ 20 deg C/D |
| Kovats Retention Index | 1549.9 1579.2 |
| Other Experimental Properties | Hygroscopic |
| Chemical Classes | Pesticides -> Organophosphate Insecticides |
COMPUTED DESCRIPTORS
| Molecular Weight | 290.19 g/mol |
|---|---|
| XLogP3 | 0.4 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 10 |
| Exact Mass | 290.06842697 g/mol |
| Monoisotopic Mass | 290.06842697 g/mol |
| Topological Polar Surface Area | 80.3 Ų |
| Heavy Atom Count | 17 |
| Formal Charge | 0 |
| Complexity | 246 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Tetraethyl pyrophosphate is an organic phosphate pesticide which acts as an inhibitor of cholinesterase, and as such it is highly toxic by all routes of exposure. It is a water-white to amber liquid, depending on purity. Tetraethyl pyrophosphate is soluble in water and is slowly decomposed by water. It is toxic by inhalation and by skin absorption. It may be found as a liquid or as a dry mixture where the liquid is absorbed onto a dry carrier.