89796-99-6
Product Name:
Aceclofenac
Formula:
C16H13Cl2NO4
Synonyms:
2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid carboxymethyl ester;;Aceclofenac
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Melting Point | 149-153 |
|---|---|
| Solubility | >53.1 [ug/mL] (The mean of the results at pH 7.4) |
| LogP | 2.17 |
SAFETY INFORMATION
| Signal word | Danger |
|---|---|
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Environment GHS09 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H319:Serious eye damage/eye irritation H410:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P273:Avoid release to the environment. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
COMPUTED DESCRIPTORS
| Molecular Weight | 354.2 g/mol |
|---|---|
| XLogP3 | 4.3 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 7 |
| Exact Mass | 353.0221633 g/mol |
| Monoisotopic Mass | 353.0221633 g/mol |
| Topological Polar Surface Area | 75.6 Ų |
| Heavy Atom Count | 23 |
| Formal Charge | 0 |
| Complexity | 411 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Aceclofenac is a monocarboxylic acid that is the carboxymethyl ester of diclofenac. It is an oral, biologically active non-steroidal anti-inflammatory drug (NSAID) with significant anti-inflammatory and analgesic properties for the treatment of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.