Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

Homecas88768-40-5

88768-40-5

88768-40-5 structural image
Product Name: Cilazapril
Formula: C22H31N3O5
Synonyms: Cilastatin sodium;Cilazapril monohydrate
Inquiry

CHEMICAL AND PHYSICAL PROPERTIES

Physical Description Solid
Melting Point 98 ºC with decomposition
Solubility Water (25 ºC) 0.5 g/100 mL
LogP 0.8

SAFETY INFORMATION

Signal word Warning
Pictogram(s)

Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

COMPUTED DESCRIPTORS

Molecular Weight 417.5 g/mol
XLogP3 0.6
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 7
Rotatable Bond Count 9
Exact Mass 417.22637110 g/mol
Monoisotopic Mass 417.22637110 g/mol
Topological Polar Surface Area 99.2 Ų
Heavy Atom Count 30
Formal Charge 0
Complexity 608
Isotope Atom Count 0
Defined Atom Stereocenter Count 3
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Cilazapril is a pyridazinodiazepine resulting from the formal condensation of the carboxy group of cilazaprilat with ethanol. It is a drug used in the treatment of hypertension and heart failure. It has a role as a prodrug, an antihypertensive agent and an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor. It is an ethyl ester, a pyridazinodiazepine and a dicarboxylic acid monoester. It is functionally related to a Cilazaprilat.

RELATED SUPPLIERS

Glenmark Pharmaceuticals Limited

1Y
product:88768-40-5 Cilazapril 98%

Hetero Drugs Limited

1Y
product:88768-40-5 98%

Sun Pharmaceutical Industries Ltd

1Y
product:Cilazapril 98%
All suppliers(3)