62229-50-9
Product Name:
EPIDERMAL GROWTH FACTOR, HUMAN
Formula:
C257H381N73O83S7
Synonyms:
EGF;Epidermal Growth Factor;Epidermal Growth Factor, Human, Recombinant, E. coli;EGF, Human, Recombinant, E. coli;EGF, Murine Submaxillary Glands, Receptor Grade
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COMPUTED DESCRIPTORS
| Molecular Weight | 6046 g/mol |
|---|---|
| XLogP3 | -19.6 |
| Hydrogen Bond Donor Count | 96 |
| Hydrogen Bond Acceptor Count | 96 |
| Rotatable Bond Count | 193 |
| Exact Mass | 6043.5948607 g/mol |
| Monoisotopic Mass | 6041.5881511 g/mol |
| Topological Polar Surface Area | 2560 Ų |
| Heavy Atom Count | 420 |
| Formal Charge | 0 |
| Complexity | 15400 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 51 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
A 6-kDa polypeptide growth factor initially discovered in mouse submaxillary glands. Human epidermal growth factor was originally isolated from urine based on its ability to inhibit gastric secretion and called urogastrone. Epidermal growth factor exerts a wide variety of biological effects including the promotion of proliferation and differentiation of mesenchymal and EPITHELIAL CELLS. It is synthesized as a transmembrane protein which can be cleaved to release a soluble active form.