524-36-7
Product Name:
Pyridoxamine dihydrochloride
Formula:
C8H14Cl2N2O2
Synonyms:
4-(Aminomethyl)-5-hydroxy-6-methyl-3-pyridinemethanol dihydrochloride;Pyridoxamine, Dihydrochloride - CAS 524-36-7 - Calbiochem
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
Physical Description | Solid; [Merck Index] White to off-white solid; [Acros Organics MSDS] |
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Vapor Pressure | 0.00000144 [mmHg] |
Chemical Classes | Biological Agents -> Vitamins and Derivatives |
SAFETY INFORMATION
Signal word | Warning |
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Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
COMPUTED DESCRIPTORS
Molecular Weight | 241.11 g/mol |
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Hydrogen Bond Donor Count | 5 |
Hydrogen Bond Acceptor Count | 4 |
Rotatable Bond Count | 2 |
Exact Mass | 240.0432331 g/mol |
Monoisotopic Mass | 240.0432331 g/mol |
Topological Polar Surface Area | 79.4 Ų |
Heavy Atom Count | 14 |
Formal Charge | 0 |
Complexity | 143 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 3 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Pyridoxamine dihydrochloride is a hydrochloride obtained by combining pyridoxamine with two molar equivalents of hydrochloric acid. Used for treatment of diabetic nephropathy. It has a role as an Escherichia coli metabolite, a Saccharomyces cerevisiae metabolite, a human metabolite, a mouse metabolite, a plant metabolite, an iron chelator and a nephroprotective agent. It is a hydrochloride and a vitamin B6. It contains a pyridoxamine(2+).