2920-86-7
Product Name:
Prednisolone succinate
Formula:
C25H32O8
Synonyms:
Δ1-Hydrocortisone 21-hemisuccinate;(11β)-11,17-Dihydroxy-21-[(3,3-dimethyl-1-oxobutyl)oxy]pregna-1,4-diene-3,20-dione;1,4-Pregnadiene-11β,17,21-triol-3,20-dione 21-hemisuccinate;11β,17α,21-Trihydroxy-1,4-pregnadiene-3,20-dione 21-hemisuccinate;Prednisolone 21-hemisuccinate
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
Collision Cross Section | 210.3 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards] |
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SAFETY INFORMATION
Signal word | Danger |
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Pictogram(s) |
Health Hazard GHS08 |
Precautionary Statement Codes |
P201:Obtain special instructions before use. P280:Wear protective gloves/protective clothing/eye protection/face protection. P308+P313:IF exposed or concerned: Get medical advice/attention. |
COMPUTED DESCRIPTORS
Molecular Weight | 460.5 g/mol |
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XLogP3 | 1.8 |
Hydrogen Bond Donor Count | 3 |
Hydrogen Bond Acceptor Count | 8 |
Rotatable Bond Count | 7 |
Exact Mass | 460.20971797 g/mol |
Monoisotopic Mass | 460.20971797 g/mol |
Topological Polar Surface Area | 138 Ų |
Heavy Atom Count | 33 |
Formal Charge | 0 |
Complexity | 950 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 7 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Prednisolone succinate is a hemisuccinate resulting from the formal condensation of the 21-hydroxy group prednisolone with one of the carboxy groups of succinic acid. It is used to treat mild to moderate non-infectious eye allergies and inflammation, including damage caused by chemical and thermal burns. It has a role as an anti-inflammatory drug. It is a hemisuccinate, an 11beta-hydroxy steroid, a 17alpha-hydroxy steroid, a 20-oxo steroid, a 3-oxo-Delta(1),Delta(4)-steroid and a tertiary alpha-hydroxy ketone. It is functionally related to a prednisolone and a succinic acid. It is a conjugate acid of a prednisolone succinate(1-).