1397-89-3
Product Name:
Amphotericin B
Formula:
C47H73NO17
Synonyms:
Amphotericin;Amphotericin B;Amphotericin B from Streptomyces sp.;Fungizone
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Amphotericin b is a bright yellow powder. (NTP, 1992) |
|---|---|
| Color/Form | Deep yellow prisms or needles from n,n-dimethylformamide |
| Odor | ODORLESS OR PRACTICALLY SO |
| Melting Point | greater than 338 °F (decomposes) (NTP, 1992) |
| Solubility | less than 1 mg/mL at 70 °F (NTP, 1992) |
| LogP | 0.8 |
| Stability/Shelf Life | Solids and solutions appear stable for long periods between pH 4 and 10 when stored at moderate temperature out of light and air. |
| Optical Rotation | Specific optical rotation at 24 °C/D: +333 deg (acidic N,N-dimethylformamide); -33.6 deg (0.1 N methanolic hydrochloric acid) |
| Decomposition | When heated to decomposition it emits toxic fumes of /nitrogen oxides/. |
SAFETY INFORMATION
| Signal word | Danger |
|---|---|
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H372:Specific target organ toxicity, repeated exposure |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P314:Get medical advice/attention if you feel unwell. P501:Dispose of contents/container to..… |
COMPUTED DESCRIPTORS
| Molecular Weight | 924.1 g/mol |
|---|---|
| XLogP3 | 0 |
| Hydrogen Bond Donor Count | 12 |
| Hydrogen Bond Acceptor Count | 18 |
| Rotatable Bond Count | 3 |
| Exact Mass | 923.48784986 g/mol |
| Monoisotopic Mass | 923.48784986 g/mol |
| Topological Polar Surface Area | 320 Ų |
| Heavy Atom Count | 65 |
| Formal Charge | 0 |
| Complexity | 1670 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 19 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 7 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Amphotericin b is a bright yellow powder. (NTP, 1992)