Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

Homecas122852-69-1

122852-69-1

122852-69-1 structural image
Product Name: Alosetron hydrochloride
Formula: C17H19ClN4O
Synonyms: 2,3,4,5-Tetrahydro-5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H-pyrido[4,3-b]indol-1-one hydrochloride
Inquiry

CHEMICAL AND PHYSICAL PROPERTIES

Melting Point 288-291 °C
Solubility White to beige solid with a solubility of 61 mg/ml in water, 42 mg/ml in 0.1M hydrochloric acid, 0.3 mg/ml in pH 6 phosphate buffer, and <0.1 mg/ml in pH 8 phosphate buffer /Hydrochloride/
Other Experimental Properties Mol wt: 294.35. /Alosetron/

SAFETY INFORMATION

Signal word Danger
Pictogram(s)

Skull and Crossbones
Acute Toxicity
GHS06
GHS Hazard Statements H301:Acute toxicity,oral
H319:Serious eye damage/eye irritation
H412:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P273:Avoid release to the environment.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

COMPUTED DESCRIPTORS

Molecular Weight 330.8 g/mol
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 2
Rotatable Bond Count 2
Exact Mass 330.1247389 g/mol
Monoisotopic Mass 330.1247389 g/mol
Topological Polar Surface Area 53.9 Ų
Heavy Atom Count 23
Formal Charge 0
Complexity 442
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 2
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Alosetron Hydrochloride is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist. Alosetron blocks the actions of serotonin at 5-HT3 sites in the peripheral nervous system, particularly on enteric and nociceptive sensory neurons, thereby affecting the regulation of visceral pain, decreasing gastrointestinal contraction and motility, and decreasing gastrointestinal secretions. This agent is used to treat diarrhea-predominant irritable bowel syndrome in women.

RELATED SUPPLIERS

Cipla Ltd

1Y
product:122852-69-1 Alosetron hydrochloride 98%

Nuray Chemicals Pvt Ltd

1Y
product:Alosetron hydrochloride 98%

Aruvi Labs

1Y
product:Alosetron hydrochloride 98%

Biophore India Pharmaceuticals Pvt Ltd

1Y
product:Alosetron hydrochloride 122852-69-1 98%

KPS Chemicals And Pharmaceuticals

1Y
product:Alosetron hydrochloride 98%

Cipla Ltd.

Maharashtra
product:Alosetron hydrochloride

Aruvi Labs

Tamil Nadu
product:Alosetron hydrochloride
All suppliers(7)