106-49-0

Product Name: p-Toluidine

Formula: C7H9N

Synonyms: p-Toluidine;4-Aminotoluene;4-Aminotoluene, 4-Methylaniline;4-Methylaniline

Inquiry

CHEMICAL AND PHYSICAL PROPERTIES SAFETY INFORMATION COMPUTED DESCRIPTORS PRODUCT INTRODUCTION RELATED SUPPLIERS

CHEMICAL AND PHYSICAL PROPERTIES

Physical Description	P-toluidine is a colorless solid. Melting point 44 °C (111 °F). Specific gravity 1.046. Vapor heavier than air. Produces toxic oxides of nitrogen during combustion. May be absorbed through the skin. Used in dyes, and in organic chemical manufacturing.
Color/Form	Lustrous plates or leaflets
Odor	Aromatic, wine-like odor
Taste	Burning taste
Boiling Point	393 °F at 760 mmHg (USCG, 1999)
Melting Point	112.1 °F (USCG, 1999)
Flash Point	188 °F (USCG, 1999)
Solubility	0.7 % (NIOSH, 2023)
Density	1 at 68 °F (USCG, 1999)
Vapor Density	3.90 (Air = 1)
Vapor Pressure	1 mmHg at 108 °F (NIOSH, 2023)
LogP	log Kow = 1.39
Henry's Law Constant	Henry's Law constant = 2.02X10-6 atm-cu m/mol at 25 °C
Autoignition Temperature	899 °F (USCG, 1999)
Decomposition	When heated to decomposition it emits highly toxic fumes of /nitroxides/.
Heat of Vaporization	44.3 kJ/mol at 200.4 °C
Ionization Potential	7.50 eV
Ionization Efficiency	Positive
Odor Threshold	Odor Threshold Low: 0.02 [mmHg] Odor Threshold High: 3.2 [mmHg] Odor threshold from AIHA
Refractive Index	Index of refraction: 1.5534 at 45 °C/D
Dissociation Constants	pKa = 5.10 at 25 °C (conjugate acid)
Kovats Retention Index	1042.1 1068 1092 1092 1055.3 1056.5 1037
Other Experimental Properties	Heat of fusion: 18.9 kJ/mol at 43.6 °C
Chemical Classes	Nitrogen Compounds -> Amines, Aromatic

SAFETY INFORMATION

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08 Environment GHS09
GHS Hazard Statements	H317:Sensitisation, Skin H319:Serious eye damage/eye irritation H351:Carcinogenicity H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

COMPUTED DESCRIPTORS

Molecular Weight	107.15 g/mol
XLogP3	1.4
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	0
Exact Mass	107.073499291 g/mol
Monoisotopic Mass	107.073499291 g/mol
Topological Polar Surface Area	26 Å²
Heavy Atom Count	8
Formal Charge	0
Complexity	62.8
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

PRODUCT INTRODUCTION

description

P-toluidine is a colorless solid. Melting point 44 °C (111 °F). Specific gravity 1.046. Vapor heavier than air. Produces toxic oxides of nitrogen during combustion. May be absorbed through the skin. Used in dyes, and in organic chemical manufacturing.