CHEMICAL AND PHYSICAL PROPERTIES
Melting Point | >193ºC |
---|---|
Solubility | <1 mg/ml |
LogP | 3.79 |
Dissociation Constants | 7.34 |
COMPUTED DESCRIPTORS
Molecular Weight | 505.6 g/mol |
---|---|
XLogP3 | 4.6 |
Hydrogen Bond Donor Count | 1 |
Hydrogen Bond Acceptor Count | 8 |
Rotatable Bond Count | 8 |
Exact Mass | 505.22128572 g/mol |
Monoisotopic Mass | 505.22128572 g/mol |
Topological Polar Surface Area | 114 Ų |
Heavy Atom Count | 37 |
Formal Charge | 0 |
Complexity | 933 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 2 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Benidipine has the formula 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridine-dicarboxylic acid methyl 1-(phenylmethyl)-3-piperidinyl ester hydrochloride. It is a synthetic dihydropyridine derivative that has anti-hypertensive and anti-anginal actions. It was originated in Japan by Kyowa Hakko, it is submitted for FDA approval and it is currently available in some Asian countries like India and Japan.