Trimethyl phosphonoacetate
Synonym(s):(Carboxymethyl)phosphonic acid trimethyl ester;NSC 84262
- CAS NO.：5927-18-4
- Empirical Formula: C5H11O5P
- Molecular Weight: 182.11
- MDL number: MFCD00008452
- EINECS: 227-663-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-04-23 16:18:34
What is Trimethyl phosphonoacetate?
The Uses of Trimethyl phosphonoacetate
Trimethyl phosphonoacetate is used in the preparation of sarin A by intramolecular Mannich-type reactions. It is involved in the Horner-Wadsworth-Emmons olefination with aldehydes and ketones to give acrylic esters. It is also involved in oxa-Michael reactions, prenylation of oxindoles and heterocyclization reactions.
Properties of Trimethyl phosphonoacetate
| Melting point: | 242 °C |
| Boiling point: | 118 °C0.85 mm Hg(lit.) |
| Density | 1.125 g/mL at 25 °C(lit.) |
| Flash point: | >230 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | Liquid |
| color | Clear colorless to light yellow |
| Water Solubility | Slightly miscible with water. |
Safety information for Trimethyl phosphonoacetate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H227:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for Trimethyl phosphonoacetate
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JSK Chemicals
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product: 5927-18-4 Trimethyl phosphonoacetate, 97% 99%
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