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HomeProduct name listTrifluoroacetamide

Trifluoroacetamide

Synonym(s):2,2,2-Trifluoroacetamide

  • CAS NO.:354-38-1
  • Empirical Formula: C2H2F3NO
  • Molecular Weight: 113.04
  • MDL number: MFCD00008008
  • EINECS: 206-559-9
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-05-30 16:33:02
Trifluoroacetamide Structural Picture

What is Trifluoroacetamide?

The Uses of Trifluoroacetamide

2,2,2-Trifluoroacetamide used in a convenient alternative to the Gabriel synthesis of primary amines from halides by N-alkylation followed by cleavage of the readily-hydrolyzed trifluoroacetyl group and for improved N-alkylation under phase-transfer conditions allowing successive alkylation with different alkyl groups.

Properties of Trifluoroacetamide

Melting point: 65-70 °C (lit.)
Boiling point: 162.5 °C (lit.)
Density  1.4176 (estimate)
Flash point: 162-164°C
storage temp.  Store below +30°C.
solubility  460 g/L (20°C)
form  Crystalline Powder or Crystals
color  White to pale yellow or beige
Water Solubility  460 g/L (20 ºC)

Safety information for Trifluoroacetamide

Signal word Warning
Pictogram(s)

Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Trifluoroacetamide

InChIKey NRKYWOKHZRQRJR-UHFFFAOYSA-N

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