Trichloroacetic acid
Synonym(s):TCA;Trichloroacetic acid;Trichloroacetic Acid - CAS 76-03-9 - Calbiochem
- CAS NO.:76-03-9
- Empirical Formula: C2HCl3O2
- Molecular Weight: 163.39
- MDL number: MFCD00004177
- EINECS: 200-927-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-11-28 16:31:44
What is Trichloroacetic acid?
The Uses of Trichloroacetic acid
Protein precipitation reagentTrichloroacetic acid is used as a precipitating agent in biochemistry for precipitation of proteins, DNA and RNA. It is an active ingredient used in cosmetic treatments like chemical peels, tattoo removal and the treatment of warts including genital warts. It is also used to determine protein concentration and as a decalcifier and fixative in microscopy.
Background
Trichloroacetate, or trichloroacetic acid, is a strong acid prepared by the reaction of chlorine with acetic acid in the presence of a suitable catalyst. In clinical chemistry and biochemistry, it is used as a precipitant of macromolecules including proteins, DNA and RNA. Trichloroacetate is also found in cosmetic treatments and topical formulations as a cauterant, which removes condyloma or warts on the skin.
What are the applications of Application
Trichloroacetic acid is an acetic acid analogue commonly used to precipitate proteins, DNA and RNA
Metabolism
Not Available
Properties of Trichloroacetic acid
Melting point: | 54-58 °C (lit.) |
Boiling point: | 196 °C (lit.) |
Density | 1.62 g/mL at 25 °C (lit.) |
Flash point: | 196°C |
storage temp. | Store at +15°C to +25°C. |
solubility | H2O: 0.5 M at 20 °C, clear, colorless |
form | Solid |
color | White |
Water Solubility | 120 g/100 mL (20 ºC) |
Sensitive | Hygroscopic |
Safety information for Trichloroacetic acid
Signal word | Danger |
Pictogram(s) |
Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07 Environment GHS09 |
GHS Hazard Statements |
H314:Skin corrosion/irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H410:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Trichloroacetic acid
Abamectin manufacturer
Bhakti Impex
JSK Chemicals
Sujan Chemicals Industries
Anugrah IN ORG Pvt Limited
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