Thiamine hydrochloride
Synonym(s):Thiamine hydrochloride;Thiamine chloride hydrochloride;Thiamine, Hydrochloride - CAS 67-03-8 - Calbiochem;Thiamio hydrochloridum;Vitamin B?
- CAS NO.:67-03-8
- Empirical Formula: C12H17N4OS.ClH.Cl
- Molecular Weight: 337.27
- MDL number: MFCD00012780
- EINECS: 200-641-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-05-10 17:26:08
What is Thiamine hydrochloride?
Description
In 1912, Cashmir Funk isolated thiamine from rice husks and coined the term ‘vitamine’ because it was required for life (‘vita’) and because thiamine contained nitrogen (‘amine’). Thiamine, formerly known as B1, is water soluble. Thiamine is a vital cofactor for enzymes and coenzymes of glycolysis, the Kreb’s cycle, the pentose phosphate pathway. Thiamine is also involved in the biosynthesis of the neurotransmitters acetylcholine and gamma-aminobutyric acid and in nerve propagation.
The Uses of Thiamine hydrochloride
Thiamine is the water-soluble vitamin b1, required for normal digestion and functioning of nerve tissues and in the prevention of beriberi. It also acts as a coenzyme in the metabolism of carbohydrates. During processing, the higher and longer the heating period, the greater the loss. The loss is reduced in the presence of acid. Thiamine hydrochloride and thiamine mononitrate are two available forms. The mononitrate form is less hygroscopic and more stable than the hydrochloride form, making it suitable for use in beverage powders. It is used in enriched flour and is found as thiamine mononitrite in frozen egg substitute and crackers.
What are the applications of Application
Thiamine, Hydrochloride is a cofactor required for oxidation of carbohydrates and for the synthesis of ribose
Properties of Thiamine hydrochloride
Melting point: | 250 °C (dec.)(lit.) |
Density | 1.3766 (rough estimate) |
Flash point: | 9°C |
storage temp. | room temp |
solubility | H2O: 0.1 g/mL at 20 °C, clear, colorless |
form | Crystalline Powder |
color | White to almost white |
Water Solubility | 1 g/mL |
Sensitive | Light Sensitive & Hygroscopic |
Safety information for Thiamine hydrochloride
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H319:Serious eye damage/eye irritation |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for Thiamine hydrochloride
Abamectin manufacturer
JSK Chemicals
Prachi Pharmaceuticals Pvt Ltd
Salvavidas Pharmaceutical Pvt., Ltd.
Meteoric Biopharmaceuticals Pvt. Ltd.
Mascot Industries Pvt., Ltd.
Biophore India Pharmaceuticals Pvt Ltd
Globela Industry Pvt Ltd
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