thiadiazole
- CAS NO.:288-48-2
- Empirical Formula: C2H2N2S
- Molecular Weight: 86.12
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:37

What is thiadiazole?
Description
1,2,3-Thiadiazole is a five-membered, π-excessive, stable, almost planar, unsaturated, conjugated, heteroaromatic comprised of one sulfur atom, two adjacent nitrogen atoms (S–N–N), and two carbon atoms. There are four possible noninterconvertible regioisomeric structures depending on the relative position of heteroatoms.
Physical properties
The parent 1,2,3-thiadiazole is a yellow-colored liquid with a bp of 157°C. It is a weak base, thermally stable, and soluble in water and most of the organic solvents such as alcohol, ether, DCM, and chloroform.
The Uses of thiadiazole
1,2,3-Thiadiazoles have broader applications as insecticide synergists, cross-linked polymer compounds, and herbicides. Besides agro-applications there are other applications such as sedative, antibacterial and antibiotic, antiviral, and neurodegenerative.
Definition
ChEBI: 1,2,3-thiadiazole is a thiadiazole.
Chemical Reactivity
As is evident from the electron density map on the ring atoms, both C4 and C5 carbon atoms have the least electron density compared to nitrogen, making them resistant to electrophilic attack on carbon atoms but facile to nitrogen atoms. However, nucleophilic substitution is facile to carbon atoms.
Properties of thiadiazole
Boiling point: | 110.8±23.0 °C(Predicted) |
Density | 1.317±0.06 g/cm3(Predicted) |
pka | -3.39±0.22(Predicted) |
Safety information for thiadiazole
Computed Descriptors for thiadiazole
New Products
Polycaprolactone, CL10015 , M.W: 190,000 – 240,000 da , I.V: 1.30 – 1.70 dL/g Poly(DL-Lactide)-co-Glycolide, DLG852A, M.W:7,000 - 17,000 da, I.V: 0.16 - 0.24 dL/g PLGA 50:50 – PEG, DLG501P1 ,M.W:PLGA (Mw) : ~10,000 da, PEG (Mw) : ~1500 da L-Lactide DL-Lactide 502-97-6 2-Butyn-1-oL 3-Butyn-1-oL Pyridine, 3-[4-(hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methyl-, (2E)-2-butenedioate (1:1) Di-tert-butyl dicarbonate 5-NITRONICOTINIC ACID 3-Pyridineacetonitrile, α-amino-, hydrochloride (1:1) TETRAHYDRO-2-(2-PROPYNYLOXY)-2H-PYRAN (1-Cyano-cyclobutyl)-carbamic acid tert-butyl ester CARBINOXAMINE EP IMPURITY C CHLORO ABIRATERONE OR 3-DEOXY-3- CHLOROABIRATERONE QUETIAPINE EP IMPURITY P / N-ETHYL QUETIAPINE HCL N-NITROSO AZELASTINE EP IMPURITY B (FREEZER) CLASCOTERONE EP IMPURITY A ROPIVACAINE USP RELATED COMPOUND B (HCL SALT) Bilastine Methyl 2-(4-(2-chloroethyl) phenyl)-2-methylpropanoate Meclofenoxate HCl 5-acetyl-10,11-dihydro-3-nitro-5H-dibenz[b,f]azepineYou may like
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