Quinolinic acid
Synonym(s):Quinolinic acid
- CAS NO.：89-00-9
- Empirical Formula: C7H5NO4
- Molecular Weight: 167.12
- MDL number: MFCD00006295
- EINECS: 201-874-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-05-08 14:18:51
What is Quinolinic acid?
The Uses of Quinolinic acid
Quinolinic acid is an endogenous NMDA agonist. Quinolinic acid is a metabolite of tryptophan that acts as a putative NMDA receptor agonist. Quinolinic acid is an ?excitotoxic? metabolite and an agonist of N-methyl-D-aspartate receptors. properties of KYNA raise the possibility of a functional link between KYNA and QUIN in the brain which may be of relevance for an understanding of human neurodegenerative disorders. Quinolinic acid is a potent endogenous excitant at amino acid receptors in CNS.
What are the applications of Application
Quinolinic acid is a matabolite of tryptophan and a putative NMDA receptor agonist
Properties of Quinolinic acid
| Melting point: | 188-190 °C (dec.) (lit.) |
| Boiling point: | 295.67°C (rough estimate) |
| Density | 1.5216 (rough estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | 10g/l |
| form | Crystalline Powder |
| color | White to light yellow-beige |
| Water Solubility | 0.55 g/100 mL |
Safety information for Quinolinic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Quinolinic acid
| InChIKey | GJAWHXHKYYXBSV-UHFFFAOYSA-N |
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