Quinoline
Synonym(s):1-Azanaphthalene;1-Benzazine;2,3-Benzopyridine;Quinoline
- CAS NO.:91-22-5
- Empirical Formula: C9H7N
- Molecular Weight: 129.16
- MDL number: MFCD00006736
- EINECS: 202-051-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-11-28 16:31:44
What is Quinoline?
Description
Quinoline is a colourless hygroscopic liquid with characteristic odour. On exposure
to light, it turns brown in colour. Quinoline decomposes on heating, and on burning
produces toxic fumes including nitrogen oxides. Quinoline reacts with strong oxidants,
acids, and anhydrides. Quinoline is only slightly soluble in cold water but dissolves readily
in hot water and most organic solvents. Quinoline is combustible. It gives off irritating
or toxic fumes (or gases) in a fire. Quinoline is incompatible with strong acids, oxidisers,
dinitrogen tetroxide, linseed oil, thionyl chloride, maleic anhydride, and perchromates
and reacts violently with most incompatibles. Quinoline is used extensively in the manufacturing
of dyes, preparation of hydroxyquinoline sulphate and niacin, as a solvent for
resins and terpenes, and as an intermediate in the manufacture of other products.
Quinoline is used mainly as an intermediate in the manufacture of other several products,
as a catalyst, as a corrosion inhibitor, in metallurgical processes, in the manufacture of
dyes, as a preservative for anatomical specimens, in polymers and agricultural chemicals,
and as a solvent for resins and terpenes. Quinoline is also used as an anti-malarial medicine.
Because of its solubility in water, quinoline has significant potential for mobility in the
environment, which may promote water contamination. Potential exposure to quinoline
also occurs from the inhalation of cigarette smoke. Quinoline breaks down quickly in the
atmosphere and water.
The Uses of Quinoline
Quinoline is used in the manufacture of dyesand hydroxyquinoline salts; as a solvent forresins and terpenes; and therapeutically as anantimalarial agent. It occurs in coal tar insmall amounts.
Properties of Quinoline
Melting point: | -17--13 °C (lit.) |
Boiling point: | 113-114 °C/11 mmHg (lit.)
237 °C (lit.) |
Density | 1.093 g/mL at 25 °C (lit.) |
Flash point: | 214 °F |
storage temp. | Store below +30°C. |
solubility | 6g/l |
form | Liquid |
color | Purple to dark grey |
Odor | Strong, unpleasant. |
Water Solubility | slightly soluble |
Sensitive | Light Sensitive & Hygroscopic |
Safety information for Quinoline
Signal word | Danger |
Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08 Environment GHS09 |
GHS Hazard Statements |
H301:Acute toxicity,oral H312:Acute toxicity,dermal H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H341:Germ cell mutagenicity H350:Carcinogenicity H411:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P202:Do not handle until all safety precautions have been read and understood. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Quinoline
InChIKey | SMWDFEZZVXVKRB-UHFFFAOYSA-N |
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