Pyridinium chlorochromate

The Uses of Pyridinium chlorochromate

Pyridinium chlorochromate is usually used to oxidize an allylic methylene group.
Oxidation of primary alcohols to aldehydes

Pyridinium dichromate (PDC) or pyridinium chlorochromate (PCC) in anhydrous media such as dichloromethane oxidizes primary alcohols to aldehydes while avoiding overoxidation to carboxylic acids.

The Uses of Pyridinium chlorochromate

To a solution of the SM (1.055 g, 3.23 mmol) in DCM was added PCC (0.915 g, 4.20 mmol) and celite (1.96 g). The reaction mixture was stirred at RT for 1 h 50 min, then a second portion of PCC (0.494 g, 2.30 mmol) was added. Stirring was continued for another 1 h, after which time the solids were removed via filtration through celite. The filtrate was concentrated in vacuo and the residue purified by flash chromatography (10-50% EtOAc/hexane) to provide the product as a white solid. [0.647 g, 62%] [UK Pat App GB2463151A, page 133]

What are the applications of Application

Pyridinium chlorochromate is Used to oxidize an allylic methylene group