Perindoprilat

Chemical properties

White to Off-White Solid

The Uses of Perindoprilat

Perindoprilat is the active metabolite of perindopril, an inhibitor of angiotensin converting enzyme (ACE) that has efficacy against hypertension. Perindoprilat specifically and competitively inhibits ACE in vitro with IC50 values ranging between 1.5 and 3.2 nM. Elimination of perindoprilat is decreased in the elderly and in patients with heart or renal failure.[Cayman Chemical]

The Uses of Perindoprilat

An angiotensin-converting enzyme (ACE) inhibitor. Antihypertensive.

The Uses of Perindoprilat

Perindoprilat is an angiotensin-converting enzyme (ACE) inhibitor and antihypertensive.

What are the applications of Application

Perindoprilat is an angiotensin-converting enzyme (ACE) inhibitor

Definition

ChEBI: Perindoprilat is a dipeptide obtained by formal condensation of one of the carboxy groups of N-[(1S)-1-carboxyethyl]-L-norvaline with the amino group of (2S,3aS,7aS)-octahydroindole-2-carboxylic acid. The major active metabolite of perindopril. It has a role as an antihypertensive agent, an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor and a drug metabolite. It is an organic heterobicyclic compound, a dipeptide, a dicarboxylic acid and a L-alanine derivative.