Nicotinamide

Description

Nicotinamide is a form of vitamin B3. It is essential for the function of fats and sugars in the body and for maintaining healthy cells. A white, crystalline powder. It is odorless or nearly so, and has a bitter taste. Its solutions are neutral to litmus. One g dissolves in about 1 mL of water, in about 1.5 mL of alcohol, and in about 10 mL of glycerin. Nicotinamide is used to treat or prevent diseases associated with vitamin B3 deficiency and pellagra. It is also used in the treatment of acne, diabetes, cancer, osteoarthritis, skin aging, skin discolouration and many other conditions, but there is a lack of adequate data to support this.

The Uses of Nicotinamide

Niacinamide is a nutrient and dietary supplement that is an available form of niacin. Nicotinic acid is pyridine beta-carboxylic acid and nicotinamide, which is another term for niacinamide, is the corresponding amide. It is a powder of good water solubility, having a solubility of 1 g in 1 ml of water. Unlike niacin, it has a bitter taste; the taste is masked in the encapsulated form. Used in fortification of cereals, snack foods, and powdered beverages.

Background

An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.

What are the applications of Application

Nicotinamide is an NAD+ and NADP+ coenzyme precursor

Metabolism

Not Available